BP
BP's Research: Sustainable Catalysis for C-H Activation
RESEARCH INTEREST
TM
Transition Metal Catalysis
Transition metal catalysis is the most convenient way to activate chemically inert bonds. Most traditional transition-metal catalysts are based on platinum group metals like Pt, Rh, Ir, etc. But these are very costly and often show heavy metal toxicity. Most of the ligands frequently used are phosphene-based and show volatility and toxicity. So, discovering alternative inexpensive metal catalysts and compatible non-toxic ligands is challenging. BP's research work aims to functionalize the organic molecules using low-cost catalysts mainly based on 3d-transition metals like iron, copper, manganese, etc.
PC
Photoredox Catalysis
Recently photo-redox chemistry has gained much interest in synthetic chemistry as an energy-economic greener pathway. The main attraction is the ease of radical generation in a much controlled way without any toxic radical initiator. BP's research area involves the discovery of new radical precursors and photo-mediated functionalization of organic molecules using them.
C-H Bond Functionalization
Directed C–H bond activation is the latest technique for the regioselective C–C and C–heteroatom bond formation from an unfunctionalized molecule. Proximal C–H bond functionalization is well explored but the remote C–H bond functionalization still faces several challenges like the usage of large templet to trigger a metal-catalyst towards a distal position which is not step-economical too often. BP’s research aims to find the smaller transient directing groups and the compatible catalysts to gain stereo- and regioselective distal C–H bond functionalization of arenes and heteroarenes.
Ongoing Project
Transition Metal Catalyzed Remote C–H bond Chalcogenetion of Electron-deficient Arenes